Utilization and impact of adjuvant therapy in anaplastic oligodendroglioma: an analysis on 1692 patients

The aim of this study was to determine the utilization rates and impact of adjuvant therapy on overall survival (OS) for anaplastic oligodendroglioma (AO). Data were extracted from the National Cancer Data Base (NCDB). Chi square test, Kaplan–Meier method, and Cox regression models were employed in...

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Veröffentlicht in:Journal of neuro-oncology 2016-09, Vol.129 (3), p.567-575
Hauptverfasser: Shin, Jacob Y., Diaz, Aidnag Z.
Format: Artikel
Sprache:eng
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Zusammenfassung:The aim of this study was to determine the utilization rates and impact of adjuvant therapy on overall survival (OS) for anaplastic oligodendroglioma (AO). Data were extracted from the National Cancer Data Base (NCDB). Chi square test, Kaplan–Meier method, and Cox regression models were employed in SPSS 22.0 (Armonk, NY: IBM Corp.) for data analyses. 1692 patients with AO who underwent surgery were identified. 945 (55.9 %) received adjuvant radiotherapy with concomitant chemotherapy (chemoRT), 102 (6.0 %) adjuvant radiotherapy (RT) sequentially followed by chemotherapy, 244 (14.4 %) adjuvant RT alone, and 401 (23.7 %) received no adjuvant therapy. Patients were more likely to receive adjuvant chemoRT if they were diagnosed in 2009-2013 vs. 2004–2008 (p 70 vs.
ISSN:0167-594X
1573-7373
DOI:10.1007/s11060-016-2212-z