GI highlights from the literature

Wilson's disease (WD) is an autosomal recessive disorder, which develops due to gene mutations in the copper transporter ATPase copper-transporting [beta] (Atp7b), impairing copper excretion into bile and resulting in copper accumulation in the liver. [...]novel medical therapies for this cohor...

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Veröffentlicht in:Gut 2016-10, Vol.65 (10), p.1777-1778
1. Verfasser: McLean, Mairi H
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description Wilson's disease (WD) is an autosomal recessive disorder, which develops due to gene mutations in the copper transporter ATPase copper-transporting [beta] (Atp7b), impairing copper excretion into bile and resulting in copper accumulation in the liver. [...]novel medical therapies for this cohort would be clinically useful. Overall, these data suggest that inflammasome function is vital in driving colitis-associated cancer with impaired O-glycosylation.\n The presented observational study indicates that vitamin D status is a potential independent risk factor for worse IBD outcomes and should therefore be monitored and treated.
doi_str_mv 10.1136/gutjnl-2016-312758
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source BMJ Journals - NESLi2; PubMed Central
subjects Cancer
Copper
Gastroenterology
Hepatology
Homeostasis
Hydrocarbons
Inflammatory bowel disease
Liver diseases
Metabolism
Mutation
Rodents
Studies
Transplants & implants
Tumors
Vitamin D
title GI highlights from the literature
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