Towards an Integrative Picture of Human Sickness Behavior

Towards an Integrative Picture of Human Sickness Behavior

Highlights • A random-effects meta-analysis of human sickness behavior research was conducted. • Three pro-inflammatory cytokines show significant associations with sickness behavior. • IL-6 shows the strongest association with sickness behavior. • TNF-α is understudied in this literature. • High in...

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Veröffentlicht in:Brain, behavior, and immunity behavior, and immunity, 2016-10, Vol.57, p.255-262
Hauptverfasser: Shattuck, Eric C, Muehlenbein, Michael P
Format: Artikel
Sprache:eng
Schlagworte:
Allergy and Immunology
Cytokines
Depression
Depression - blood
Humans
Illness Behavior
Interleukin-1beta - blood
Interleukin-6 - blood
Meta-analysis
Psychiatry
Psychoneuroimmunology
Sickness behavior
Tumor Necrosis Factor-alpha - blood
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Beschreibung
Zusammenfassung:Highlights • A random-effects meta-analysis of human sickness behavior research was conducted. • Three pro-inflammatory cytokines show significant associations with sickness behavior. • IL-6 shows the strongest association with sickness behavior. • TNF-α is understudied in this literature. • High inter-study heterogeneity characterizes the literature.
ISSN:0889-1591
1090-2139
DOI:10.1016/j.bbi.2016.05.002