A Clinical Risk Score to Improve the Diagnosis of Tachycardia-Induced Cardiomyopathy in Childhood

Abstract Tachycardia-induced cardiomyopathy (TIC) is a treatable cause of heart failure in children, but there is little information as to which clinical variables best discriminate TIC from other forms of cardiomyopathy. TIC cases with dilated cardiomyopathy (DC) from 16 participating centers were...

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Veröffentlicht in:	The American journal of cardiology 2016-10, Vol.118 (7), p.1074-1080
Hauptverfasser:	Moore, Jeremy P., MD, MS, Wang, Shuo, MD, Albers, Erin L., MD, MSc, Salerno, Jack C., MD, Stephenson, Elizabeth A., MD, MSc, FHRS, Shah, Maully J., MBBS, Pflaumer, Andreas, MD, Czosek, Richard J., MD, Garnreiter, Jason M., MD, Collins, Kathryn, MD, Papez, Andrew L., MD, Sanatani, Shubhayan, MD, FRCPC, Cain, Nicole B., MD, Kannankeril, Prince J., MD, MSc, Perry, James C., MD, Mandapati, Ravi, MD, FHRS, Silva, Jennifer N.A., MD, Balaji, Seshadri, MBBS, MRCP (UK), PhD, Shannon, Kevin M., MD
Format:	Artikel
Sprache:	eng
Schlagworte:	Biopsy Cardiac arrhythmia Cardiomyopathy Cardiomyopathy, Dilated - diagnostic imaging Cardiomyopathy, Dilated - drug therapy Cardiomyopathy, Dilated - etiology Cardiotonic Agents - therapeutic use Cardiovascular Case-Control Studies Child Child, Preschool Echocardiography Electrocardiography Female Heart failure Heart Failure - diagnostic imaging Heart Failure - drug therapy Heart Failure - etiology Heart Rate Humans Infant Logistic Models Logistics Male Morphology Multivariate Analysis Patients Registries Risk Assessment Sinuses Stroke Volume Tachycardia - complications Tachycardia - diagnosis Variables
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Zusammenfassung:	Abstract Tachycardia-induced cardiomyopathy (TIC) is a treatable cause of heart failure in children, but there is little information as to which clinical variables best discriminate TIC from other forms of cardiomyopathy. TIC cases with dilated cardiomyopathy (DC) from 16 participating centers were identified and compared to controls with other forms of DC. Presenting clinical, echocardiographic, and electrocardiographic (ECG) characteristics were collected. Heart rate (HR) percentile was defined as HR/median HR for age, and PR index as the PR/RR interval. P-wave morphology (PWM) was defined as possible sinus or non-sinus based on a predefined algorithm. Eighty TIC cases and 135 controls were identified. Cases demonstrated lower z-scores for LVEDD and LVESD than DC controls (4.3 vs 6.5, p
ISSN:	0002-9149 1879-1913
DOI:	10.1016/j.amjcard.2016.07.008