Association of impaired renal function and poor prognosis in oropharyngeal squamous cell carcinoma

Background Renal function influences decisions regarding treatment for patients with oropharyngeal squamous cell carcinoma (SCC). However, the importance of renal function in oropharyngeal SCC has not yet been reported. Methods Four hundred sixty patients with oropharyngeal SCC treated with curative...

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Veröffentlicht in:Head & neck 2016-10, Vol.38 (10), p.1495-1500
Hauptverfasser: Homma, Akihiro, Hayashi, Ryuichi, Kawabata, Kazuyoshi, Fujii, Takashi, Iwae, Shigemichi, Hasegawa, Yasuhisa, Nibu, Kenichi, Kato, Takakuni, Shiga, Kiyoto, Matsuura, Kazuto, Monden, Nobuya, Fujii, Masato
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Sprache:eng
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Zusammenfassung:Background Renal function influences decisions regarding treatment for patients with oropharyngeal squamous cell carcinoma (SCC). However, the importance of renal function in oropharyngeal SCC has not yet been reported. Methods Four hundred sixty patients with oropharyngeal SCC treated with curative intent between April 2005 and March 2007 in 12 institutions in Japan were analyzed retrospectively. Results Four hundred three patients (87.6%) showed a creatinine clearance (CrCl) ≥50 mL/min and 57 (12.4%) with a CrCl
ISSN:1043-3074
1097-0347
DOI:10.1002/hed.24467