Pudendal Neuralgia: A New Option for Treatment? Preliminary Results on Feasibility and Efficacy

Objective The aim of this prospective study was to investigate the feasibility and report the short‐term results of a new procedure for treatment of pudendal neuralgia, consisting of transperineal injections of autologous adipose tissue with stem cells along the Alcock's canal. Methods Fifteen women with pudendal neuralgia not responsive to 3‐months medical therapy were examined clinically, with VAS score, validated SF‐36 questionnaire, and pudendal nerve motor terminal latency (PNMTL). These patients were submitted to pudendal nerve lipofilling. Clinical examinations with VAS, SF36, and PNTML were scheduled during 12 months follow‐up, with the incidence of pain recurrence (VAS > 5) as primary outcome measure. Appropriate tests were used for statistics. Results All patients had preoperative increase of pudendal nerve latencies. Twelve patients completed the follow‐up protocol. There was no mortality, and no complications. Two patients had no pain improvement and continued to use analgesic drugs. At 12 months VAS significantly improved (3.2 ± 0.6 vs 8.1 ± 0.9, P