Validation of the American Society for Reproductive Medicine guidelines/recommendations in white European men presenting for couple's infertility

Objective To retrospectively validate the American Society for Reproductive Medicine (ASRM) guidelines/recommendations concerning endocrine evaluation in a cohort of white European men presenting for couple's infertility. Design Retrospective study. Setting Academic reproductive medicine outpatient clinic. Patient(s) Cohort of 1,056 consecutive infertile men (noninterracial infertile couples). Intervention(s) Testicular volume was assessed with a Prader orchidometer. Serum hormones were measured (8–10 a.m. ) in all cases. Hypogonadism was defined as total T < 3 ng/mL, according to the Endocrine Society definition. Semen analysis values were assessed based on the 2010 World Health Organisation reference criteria. Main Outcome Measure(s) ASRM indications for endocrine assessment in infertile men (sperm concentration