Microwave-assisted extraction of polysaccharides from Cyphomandra betacea and its biological activities

•Microwave-assisted the extraction of polysaccharides from Cyphomandra betacea.•Optimization was carried out for the isolation of polysaccharides from Cyphomandra betacea using RSM.•This Polysaccharides revealed better antioxidant activity and anti-cancer activity. Response Surface Methodology (RSM)...

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Veröffentlicht in:	International journal of biological macromolecules 2016-11, Vol.92, p.682-693
Hauptverfasser:	C, Senthil Kumar, M, Sivakumar, K, Ruckmani
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis of Variance Antineoplastic Agents - pharmacology Antioxidant Antioxidants - pharmacology Antitumor Apoptosis - drug effects Cell Line, Tumor Cell Shape - drug effects Chromatography, Liquid Cyphomandra betacea Extraction Humans Microwave Microwaves Models, Theoretical Optimisation Polysaccharides Polysaccharides - chemistry Polysaccharides - isolation & purification Polysaccharides - pharmacology Reproducibility of Results RSM Solanum - chemistry Spectrometry, Mass, Electrospray Ionization Tandem Mass Spectrometry Temperature Time Factors Water - chemistry
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Zusammenfassung:	•Microwave-assisted the extraction of polysaccharides from Cyphomandra betacea.•Optimization was carried out for the isolation of polysaccharides from Cyphomandra betacea using RSM.•This Polysaccharides revealed better antioxidant activity and anti-cancer activity. Response Surface Methodology (RSM) was used to optimize the parameters for microwave-assisted extraction of polysaccharides from Cyphomandra betacea. The results showed a good fit with a second-order polynomial equation that was statistically acceptable at P
ISSN:	0141-8130 1879-0003
DOI:	10.1016/j.ijbiomac.2016.07.062