Long-Term Survival in Patients With Acute Kidney Injury After Acute Type A Aortic Dissection Repair

Background Although acute kidney injury (AKI) is known as a serious complication after operation for acute type A aortic dissection (AAAD), the long-term impact of AKI remains unclear. The aim of the present study is to investigate the long-term survival in patients with AKI after operation for AAAD...

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Veröffentlicht in:	The Annals of thoracic surgery 2016-12, Vol.102 (6), p.2003-2009
Hauptverfasser:	Sasabuchi, Yusuke, MD, MPH, Kimura, Naoyuki, MD, PhD, Shiotsuka, Junji, MD, Komuro, Tetsuya, MD, Mouri, Hideyuki, MD, Ohnuma, Tetsu, MD, Asaka, Kayo, MD, Lefor, Alan K., MD, PhD, Yasunaga, Hideo, MD, PhD, Yamaguchi, Atsushi, MD, PhD, Adachi, Hideo, MD, PhD, Sanui, Masamitsu, MD, PhD
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute Kidney Injury - etiology Acute Kidney Injury - mortality Aged Aneurysm, Dissecting - surgery Aortic Aneurysm, Thoracic - surgery Cardiothoracic Surgery Cause of Death Comorbidity Female Follow-Up Studies Humans Japan - epidemiology Kaplan-Meier Estimate Length of Stay - statistics & numerical data Male Middle Aged Postoperative Complications - etiology Postoperative Complications - mortality Proportional Hazards Models Respiration, Artificial - utilization Retrospective Studies Risk Factors Surgery
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Zusammenfassung:	Background Although acute kidney injury (AKI) is known as a serious complication after operation for acute type A aortic dissection (AAAD), the long-term impact of AKI remains unclear. The aim of the present study is to investigate the long-term survival in patients with AKI after operation for AAAD. Methods This study included 403 patients who underwent operation for AAAD from 1990 to 2011 at Jichi Medical University, Saitama Medical Center. Postoperative AKI was identified according to the Kidney Disease Improving Global Outcomes criteria. Kaplan-Meier survival analysis and Cox proportional hazards regression were modeled to analyze the association between the AKI stage and postoperative long-term survival. Results Of 403 patients, 181 (44.9%) experienced postoperative AKI. Kaplan-Meier estimates for long-term survival were significantly different among patients without AKI and patients with stage 1, 2, and 3 AKI ( p
ISSN:	0003-4975 1552-6259
DOI:	10.1016/j.athoracsur.2016.05.006