Effect of vitamin D supplementation on endothelial dysfunction in hemodialysis patients

Introduction: Patients with chronic kidney disease (CKD) commonly experience 25‐hydroxyvitamin D3 (25‐OH‐D3) deficiency, and these patients have a higher incidence of cardiovascular diseases (CVDs) due to endothelial dysfunction (ED). The aim of our study was to investigate the effect of 25‐OH‐D3 de...

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Veröffentlicht in:	Hemodialysis international 2017-01, Vol.21 (1), p.97-106
Hauptverfasser:	Karakas, Yusuf, Sahin, Garip, Urfali, Furkan Ertürk, Bal, Cengiz, Degirmenci, Nevbahar Akcar, Sirmagul, Basar
Format:	Artikel
Sprache:	eng
Schlagworte:	25‐Hydroxyvitamin D3 Adult Aged carotid intima‐media thickness cholecalciferol Dietary Supplements - analysis endothelial dysfunction Female flow‐mediated dilatation Humans Male Middle Aged Renal Dialysis - adverse effects Renal Dialysis - methods Renal Insufficiency, Chronic - complications Vitamin D - blood Vitamin D - therapeutic use
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Zusammenfassung:	Introduction: Patients with chronic kidney disease (CKD) commonly experience 25‐hydroxyvitamin D3 (25‐OH‐D3) deficiency, and these patients have a higher incidence of cardiovascular diseases (CVDs) due to endothelial dysfunction (ED). The aim of our study was to investigate the effect of 25‐OH‐D3 deficiency and its supplementation on ED in patients with CKD. Methods: Twenty‐nine uremic patients on dialysis and 20 healthy controls were evaluated for ED by high‐resolution Doppler ultrasonography of the brachial artery. In addition, 25‐OH‐D3‐deficient patients (25‐OH‐D3
ISSN:	1492-7535 1542-4758
DOI:	10.1111/hdi.12439