The experiences of health‐related quality of life in patients with nonspecific symptoms who undergo a diagnostic evaluation for cancer: a qualitative interview study

The diagnostic phase of cancer can affect health‐related quality of life (HRQoL). The aim of this study was to investigate how patients with nonspecific symptoms experience HRQoL while undergoing diagnostic evaluations for cancer. Twenty‐one participants who had completed a fast‐track evaluation for possible cancer at one of three hospitals in the Capital Region, Denmark were interviewed 2–4 weeks after completing diagnostic evaluations. The interviews were semi‐structured and were supported by an interview guide based on the same themes as in The European Organisation for Research and Treatment of Cancer Quality of Life questionnaire (EORCT‐QLQ‐C30). Data analysis was based on qualitative content analysis by Krippendorff. The analysis generated six categories: symptoms, physical‐, role‐, emotional‐, cognitive‐ and social functioning, and the diagnostic fast‐track experience. From these categories, a main theme was identified: Health‐related quality of life is not solely affected by the diagnostic process. The results provide a comprehensive understanding of HRQoL in the diagnostic phase of possible cancer, which can be used not only to enhance evidence‐based care, but also in the interpretation of the EORTC‐QLQ‐C30 scores. Psycho‐social support with a focus on individual informational needs during the diagnostic phase may be warranted.