Epidemiology of Clostridium difficile infection in hospitalized oncology patients

Highlights • We identified risk factors for Clostridium difficile infection in oncology patients. • Risk factors evaluated included demographic variables, cancer treatment, and antibiotic use. • Age, prior blood transfusion, and receipt of specific antibiotic classes were associated with Clostridium difficile infection. • Prior history of Clostridium difficile infection (CDI) was a highly significant risk factor for CDI. • Hospitalized oncology patients may be particularly high risk for Clostridium difficile infection.