Universal influenza vaccines: a realistic option?

The extensive antigenic drift displayed by seasonal influenza viruses and the risk of pandemics caused by newly emerging antigenically distinct influenza A viruses of novel subtypes has raised considerable interest in the development of so-called universal influenza vaccines. We review options for t...

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Veröffentlicht in:	Clinical microbiology and infection 2016-12, Vol.22, p.S120-S124
Hauptverfasser:	de Vries, R.D., Altenburg, A.F., Rimmelzwaan, G.F.
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibodies Antibodies, Viral Humans Immunity Influenza Influenza A virus - classification Influenza A virus - immunology Influenza Vaccines - immunology Influenza, Human - epidemiology Influenza, Human - prevention & control Pandemics - prevention & control Seasons T lymphocytes Universal vaccine Virus vectors
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Beschreibung
Zusammenfassung:	The extensive antigenic drift displayed by seasonal influenza viruses and the risk of pandemics caused by newly emerging antigenically distinct influenza A viruses of novel subtypes has raised considerable interest in the development of so-called universal influenza vaccines. We review options for the development of universal flu vaccines and discuss progress that has been made recently.
ISSN:	1198-743X 1469-0691
DOI:	10.1016/j.cmi.2015.12.005