Cerebral vasomotor reactivity in reversible cerebral vasoconstriction syndrome

Background Altered cerebrovascular tone is implicated in reversible cerebral vasoconstriction syndrome (RCVS). We evaluated vasomotor reactivity using bedside transcranial Doppler in RCVS patients. Methods In this retrospective case-control study, middle cerebral artery (MCA) blood flow velocities w...

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Veröffentlicht in:	Cephalalgia 2017-05, Vol.37 (6), p.541-547
Hauptverfasser:	Topcuoglu, Mehmet Akif, Chan, Suk-tak, Silva, Gisele Sampaio, Smith, Eric Edward, Kwong, Kenneth K, Singhal, Aneesh Bhim
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Case-Control Studies Cerebrovascular Circulation - physiology Cerebrovascular Disorders - diagnostic imaging Cerebrovascular Disorders - physiopathology Female Humans Male Middle Aged Retrospective Studies Ultrasonography, Doppler, Transcranial - methods Vasoconstriction - physiology Vasomotor System - physiopathology Vasospasm, Intracranial - diagnostic imaging Vasospasm, Intracranial - physiopathology Young Adult
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Zusammenfassung:	Background Altered cerebrovascular tone is implicated in reversible cerebral vasoconstriction syndrome (RCVS). We evaluated vasomotor reactivity using bedside transcranial Doppler in RCVS patients. Methods In this retrospective case-control study, middle cerebral artery (MCA) blood flow velocities were compared at rest and in response to breath-hold in RCVS (n = 8), Migraineurs (n = 10), and non-headache Controls (n = 10). Hyperventilation response was measured in RCVS. Results In RCVS, Breath Holding Index (BHI) was severely reduced in seven of eight patients and 14/16 MCAs; seven of 16 MCAs showed exhausted (BHI
ISSN:	0333-1024 1468-2982
DOI:	10.1177/0333102416650706