Variance functions, detectability and bias: a re-evaluation

Variance functions, detectability and bias: a re-evaluation

Background A recent study used simulated internal quality control data (4 specimens × 40 replicates) to investigate the use of variance functions in estimating limit of blank and limit of detection, as per ISO definitions. Small systematic negative biases were found (typically

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Annals of clinical biochemistry 2017-03, Vol.54 (2), p.286-288
1. Verfasser: Sadler, William A
Format: Artikel
Sprache:eng
Schlagworte:
Analysis of Variance
Bias
Computer Simulation
Humans
Limit of Detection
Quality Control
Sample Size
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:Background A recent study used simulated internal quality control data (4 specimens × 40 replicates) to investigate the use of variance functions in estimating limit of blank and limit of detection, as per ISO definitions. Small systematic negative biases were found (typically
ISSN:0004-5632
1758-1001
DOI:10.1177/0004563216652176