Editor’s Choice-Acute versus subacute angiography in patients with non-ST-elevation myocardial infarction – the NONSTEMI trial phase I

Background: The 2015 European Society of Cardiology non-ST-elevation myocardial infarction (NSTEMI) guidelines recommend angiography within 24 h in high-risk patients with NSTEMI. An organized STEMI-like approach with pre-hospital or immediate in-hospital triage for acute coronary angiography (CAG) may be of therapeutic benefit but it remains unknown whether the patients can be properly diagnosed in the pre-hospital setting. We aim to evaluate whether it is feasible to diagnose patients with NSTEMI in the pre-hospital phase or immediately upon admission. Methods and results: We randomized 250 patients to either acute or subacute CAG (i.e.