Body adiposity and bone parameters of male rats from mothers fed diet containing flaxseed flour during lactation

Obesity and osteoporosis may have their origins in early postnatal life. This study was designed to evaluate whether flaxseed flour use during lactation period bears effect on body adiposity and skeletal structure of male rat pups at weaning. At birth, male Wistar rats were randomly assigned to cont...

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Veröffentlicht in:Journal of developmental origins of health and disease 2016-06, Vol.7 (3), p.314-319
Hauptverfasser: da Costa, C. A. S., da Silva, P. C. A., Ribeiro, D. C., Pereira, A. D. D., Santos, A. d. S. d., Maia, L. d. A., Ruffoni, L. D. G., de Santana, F. C., de Abreu, M. D. C., Boueri, B. F. d. C., Pessanha, C. R., Nonaka, K. O., Mancini-Filho, J., do Nascimento-Saba, C. C. A., Boaventura, G. T.
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Sprache:eng
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Zusammenfassung:Obesity and osteoporosis may have their origins in early postnatal life. This study was designed to evaluate whether flaxseed flour use during lactation period bears effect on body adiposity and skeletal structure of male rat pups at weaning. At birth, male Wistar rats were randomly assigned to control and experimental (FF) groups, whose dams were treated with control or flaxseed flour diet, respectively, during lactation. At 21 days of age, pups were weaned to assess body mass, length and composition by dual-energy X-ray absorptiometry. The animals were then sacrificed to carry out analysis of serum profile, intra-abdominal adipocyte morphology and femur characteristics. Differences were considered significant when P
ISSN:2040-1744
2040-1752
DOI:10.1017/S2040174415007977