Introduction of 2-octyl cyanoacrylate (Dermabond®) for incisional hernia mesh repair

Purpose We developed a new technique, sutureless mesh fixation, using 2-octyl cyanoacrylate (Dermabond ® , a surgical tissue adhesive) for incisional hernia repair. The objective of this article is to introduce the new technique and to examine whether the technique provides sufficient resistance to abdominal pressure. Methods We conducted two tests using a porcine model, a traction experiment and artificial pneumoperitoneum test. In the traction experiment, the adherence properties of Dermabond ® with mesh and peritoneum were examined using a tissue fragment from a pig. In the artificial pneumoperitoneum test, which used an incisional hernia porcine model, mesh was implanted on the peritoneum in the abdominal cavity with Dermabond ® . It was then determined whether sutureless mesh fixation could bear artificial abdominal air pressure. Results In the traction experiment, Dermabond ® , which bonded the mesh to the peritoneum, tolerated pressure up to 2.45 × 10 3 mmHg. In the artificial pneumoperitoneum test, the mesh was strongly fastened to the peritoneum by means of only Dermabond ® , and there was little air circulation even without closing the wound over the mesh. Conclusions Sutureless mesh fixation with Dermabond ® is technically feasible and promises to provide sufficient resistance to abdominal pressure.