The interaction between malaria and human immunodeficiency virus infection in severely anaemic Malawian children: a prospective longitudinal study

Objective Malaria and human immunodeficiency virus (HIV) infection are co‐prevalent in sub‐Saharan Africa and cause severe anaemia in children. Interactions between these infections occur in adults, although these are less clear in children. The aim of study was to determine their interaction in a c...

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Veröffentlicht in:	Tropical medicine & international health 2014-06, Vol.19 (6), p.698-705
Hauptverfasser:	Kyeyune, Francis X., Calis, Job C. J., Phiri, Kamija S., Faragher, Brian, Kachala, David, Brabin, Bernard J., Hensbroek, Michaël Boele
Format:	Artikel
Sprache:	eng
Schlagworte:	Anemia anemia severa anémie sévère Biological and medical sciences carga viral charge virale children Childrens health enfants General aspects HIV Human immunodeficiency virus Human protozoal diseases Human viral diseases Infectious diseases Malaria Medical sciences niños paludisme parasitaemia parasitemia Parasitic diseases parasitémie Protozoal diseases severe anaemia VIH Viral diseases Viral diseases of the lymphoid tissue and the blood. Aids viral load
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Zusammenfassung:	Objective Malaria and human immunodeficiency virus (HIV) infection are co‐prevalent in sub‐Saharan Africa and cause severe anaemia in children. Interactions between these infections occur in adults, although these are less clear in children. The aim of study was to determine their interaction in a cohort of severely anaemic children. Methods Severely anaemic Malawian children were enrolled, tested for HIV and malaria, transfused and followed for 18 months for malaria incidence. Antiretrovirals were not widely available in Malawi during the study period. Results Of 381 children (haemoglobin
ISSN:	1360-2276 1365-3156
DOI:	10.1111/tmi.12295