The prognostic role of the new entity butterfly-like facial rash and cutaneous findings in patients with crimean congo haemorrhagic fever

Background Crimean Congo Haemorrhagic Fever (CCHF) is a deadly fever caused by Nairovirus (family Bunyaviridae). It is an important public health problem in hyperendemic regions with a high mortality rate. There have been many studies on cutaneous findings in other viral infections, however, our kno...

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Veröffentlicht in:Journal of the European Academy of Dermatology and Venereology 2014-05, Vol.28 (5), p.604-608
Hauptverfasser: Pancar, G.S., Duygu, F., Kalkan, G.
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Sprache:eng
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Zusammenfassung:Background Crimean Congo Haemorrhagic Fever (CCHF) is a deadly fever caused by Nairovirus (family Bunyaviridae). It is an important public health problem in hyperendemic regions with a high mortality rate. There have been many studies on cutaneous findings in other viral infections, however, our knowledge is limited regarding CCHF. The aim of this study was to evaluate the cutaneous manifestations of CCHF and their relationship with mortality. Methods Patients who were diagnosed CCHF between April 1 and September 1, 2011 were enrolled in this study. Dermatologic examination and laboratory analysis were obtained during hospitalization. Results A new entity that is first reported in this study as a butterfly‐like facial rash was recognized in 76 patients (42.9%). It was not correlated with mortality but could coexist with other dermatological signs of CCHF. The major outcome was the increased mortality rate with other cutaneous findings (especially ecchymosis, purpura and petechia) (P 
ISSN:0926-9959
1468-3083
DOI:10.1111/jdv.12145