NONYLPHENOL EFFECTS ON HUMAN PROSTATE NON TUMORIGENIC CELLS
Highlights • Nonylphenol (NP) enhances the proliferation of non tumorigenic prostate cells. • NP interacts with estrogen receptor α. • NP shows an estrogen like action on prostate cells. • NP acts on gene expression of key molecules of prostate growth
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Veröffentlicht in: | Toxicology (Amsterdam) 2016-05, Vol.357-358, p.21-32 |
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container_title | Toxicology (Amsterdam) |
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creator | Forte, Maurizio Di Lorenzo, Mariana Carrizzo, Albino Valiante, Salvatore Vecchione, Carmine Laforgia, Vincenza De Falco, Maria |
description | Highlights • Nonylphenol (NP) enhances the proliferation of non tumorigenic prostate cells. • NP interacts with estrogen receptor α. • NP shows an estrogen like action on prostate cells. • NP acts on gene expression of key molecules of prostate growth |
doi_str_mv | 10.1016/j.tox.2016.05.024 |
format | Article |
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Di Lorenzo, Mariana ; Carrizzo, Albino ; Valiante, Salvatore ; Vecchione, Carmine ; Laforgia, Vincenza ; De Falco, Maria</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c540t-79ed9ce65fa2dc34600ab5d20e7e23fe46b8c59631394efe7cdcef4c16922d433</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2016</creationdate><topic>Biocompatibility</topic><topic>Cell Line</topic><topic>Cell Proliferation - drug effects</topic><topic>Emergency</topic><topic>Endocrine disrupting chemicals (EDCs)</topic><topic>Endocrine Disruptors - toxicity</topic><topic>Epithelial Cells - drug effects</topic><topic>Epithelial Cells - metabolism</topic><topic>Estradiol - analogs & derivatives</topic><topic>Estradiol - pharmacology</topic><topic>Estrogen Receptor alpha - metabolism</topic><topic>Estrogen Receptor Antagonists - pharmacology</topic><topic>Estrogen Receptor beta - metabolism</topic><topic>Estrogens</topic><topic>Gene expression</topic><topic>Gene Expression Regulation - drug effects</topic><topic>Genes</topic><topic>Humans</topic><topic>Male</topic><topic>Nonylphenol</topic><topic>Phenols - toxicity</topic><topic>Prostate</topic><topic>Prostate - cytology</topic><topic>Prostate - drug effects</topic><topic>Receptors</topic><topic>Regulators</topic><topic>Toxicology</topic><topic>Xenoestrogens</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Forte, Maurizio</creatorcontrib><creatorcontrib>Di Lorenzo, Mariana</creatorcontrib><creatorcontrib>Carrizzo, Albino</creatorcontrib><creatorcontrib>Valiante, Salvatore</creatorcontrib><creatorcontrib>Vecchione, Carmine</creatorcontrib><creatorcontrib>Laforgia, Vincenza</creatorcontrib><creatorcontrib>De Falco, Maria</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>Environment Abstracts</collection><collection>Toxicology Abstracts</collection><collection>Environmental Sciences and Pollution Management</collection><collection>Environment Abstracts</collection><collection>Technology Research Database</collection><collection>Engineering Research Database</collection><collection>Civil Engineering Abstracts</collection><jtitle>Toxicology (Amsterdam)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Forte, Maurizio</au><au>Di Lorenzo, Mariana</au><au>Carrizzo, Albino</au><au>Valiante, Salvatore</au><au>Vecchione, Carmine</au><au>Laforgia, Vincenza</au><au>De Falco, Maria</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>NONYLPHENOL EFFECTS ON HUMAN PROSTATE NON TUMORIGENIC CELLS</atitle><jtitle>Toxicology (Amsterdam)</jtitle><addtitle>Toxicology</addtitle><date>2016-05-16</date><risdate>2016</risdate><volume>357-358</volume><spage>21</spage><epage>32</epage><pages>21-32</pages><issn>0300-483X</issn><eissn>1879-3185</eissn><abstract>Highlights • Nonylphenol (NP) enhances the proliferation of non tumorigenic prostate cells. • NP interacts with estrogen receptor α. • NP shows an estrogen like action on prostate cells. • NP acts on gene expression of key molecules of prostate growth</abstract><cop>Ireland</cop><pub>Elsevier Ireland Ltd</pub><pmid>27260121</pmid><doi>10.1016/j.tox.2016.05.024</doi><tpages>12</tpages><orcidid>https://orcid.org/0000-0002-4617-8360</orcidid></addata></record> |
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subjects | Biocompatibility Cell Line Cell Proliferation - drug effects Emergency Endocrine disrupting chemicals (EDCs) Endocrine Disruptors - toxicity Epithelial Cells - drug effects Epithelial Cells - metabolism Estradiol - analogs & derivatives Estradiol - pharmacology Estrogen Receptor alpha - metabolism Estrogen Receptor Antagonists - pharmacology Estrogen Receptor beta - metabolism Estrogens Gene expression Gene Expression Regulation - drug effects Genes Humans Male Nonylphenol Phenols - toxicity Prostate Prostate - cytology Prostate - drug effects Receptors Regulators Toxicology Xenoestrogens |
title | NONYLPHENOL EFFECTS ON HUMAN PROSTATE NON TUMORIGENIC CELLS |
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