NONYLPHENOL EFFECTS ON HUMAN PROSTATE NON TUMORIGENIC CELLS

Highlights • Nonylphenol (NP) enhances the proliferation of non tumorigenic prostate cells. • NP interacts with estrogen receptor α. • NP shows an estrogen like action on prostate cells. • NP acts on gene expression of key molecules of prostate growth

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Bibliographische Detailangaben
Veröffentlicht in:	Toxicology (Amsterdam) 2016-05, Vol.357-358, p.21-32
Hauptverfasser:	Forte, Maurizio, Di Lorenzo, Mariana, Carrizzo, Albino, Valiante, Salvatore, Vecchione, Carmine, Laforgia, Vincenza, De Falco, Maria
Format:	Artikel
Sprache:	eng
Schlagworte:	Biocompatibility Cell Line Cell Proliferation - drug effects Emergency Endocrine disrupting chemicals (EDCs) Endocrine Disruptors - toxicity Epithelial Cells - drug effects Epithelial Cells - metabolism Estradiol - analogs & derivatives Estradiol - pharmacology Estrogen Receptor alpha - metabolism Estrogen Receptor Antagonists - pharmacology Estrogen Receptor beta - metabolism Estrogens Gene expression Gene Expression Regulation - drug effects Genes Humans Male Nonylphenol Phenols - toxicity Prostate Prostate - cytology Prostate - drug effects Receptors Regulators Toxicology Xenoestrogens
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Beschreibung
Zusammenfassung:	Highlights • Nonylphenol (NP) enhances the proliferation of non tumorigenic prostate cells. • NP interacts with estrogen receptor α. • NP shows an estrogen like action on prostate cells. • NP acts on gene expression of key molecules of prostate growth
ISSN:	0300-483X 1879-3185
DOI:	10.1016/j.tox.2016.05.024