Stability of cocaine impurity profiles during 12 months of storage

Stability of cocaine impurity profiles during 12 months of storage

Highlights • Changes in cocaine impurity profiles under different storage conditions are examined. • Alkaloid profiles change over time and are susceptible to sample purity and elevated temperatures. • Residual solvent profiles are not affected by any of the examined experimental conditions.

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Veröffentlicht in:Forensic science international 2016-07, Vol.264, p.56-62
Hauptverfasser: Nielsen, Louise Stride, Villesen, Palle, Lindholst, Christian
Format: Artikel
Sprache:eng
Schlagworte:
Accreditation
Alkaloids
Caffeine
Cocaine
Cocaine - chemistry
Drug Contamination
Drug Stability
Drug Storage - statistics & numerical data
Forensic science
Forensic sciences
Forensic Toxicology
Gas Chromatography-Mass Spectrometry
Generalized linear models
Headspace analysis
Illicit drugs
Impurities
Laboratories
Lactose
Methods
Narcotics
Narcotics - chemistry
Pathology
Principal components analysis
Profiling
Purity
Solvents
Specimen Handling
Stability
Storage temperature
Time Factors
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Beschreibung
Zusammenfassung:Highlights • Changes in cocaine impurity profiles under different storage conditions are examined. • Alkaloid profiles change over time and are susceptible to sample purity and elevated temperatures. • Residual solvent profiles are not affected by any of the examined experimental conditions.
ISSN:0379-0738
1872-6283
DOI:10.1016/j.forsciint.2016.03.012