Sintering of Beta-Tricalcium Phosphate Scaffold Using Polyurethane Template
Porous beta-tricalcium phosphate (β-TCP) bioceramic has been reported as synthetic graft for cancellous bone substitute due to its biocompatibility and biodegradability properties. A highly porous and interconnected porosity architecture of bone scaffold facilitates attachment and in-growth of new b...
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| Veröffentlicht in: | Key Engineering Materials 2016-05, Vol.694, p.94-98 |
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| creator | Othman, Radzali Wong, Wai Yee Mohd Noor, Ahmad Fauzi |
| description | Porous beta-tricalcium phosphate (β-TCP) bioceramic has been reported as synthetic graft for cancellous bone substitute due to its biocompatibility and biodegradability properties. A highly porous and interconnected porosity architecture of bone scaffold facilitates attachment and in-growth of new bone tissue. β-TCP foam, a porous 3-dimensional scaffold was fabricated by employing polymeric foam replica method in this study. Polyurethane (PU) foam was used as the sacrificial template, in which β-TCP slurry with powder to water ratio of 10g:10ml was coated on PU template and sintered to 1100, 1200, 1250 and 1300°C. Observation on architecture of the foam, macrostructure and microstructure of pores and surface topography of porous strut showed that sintering at 1250°C produced sufficient densification of grains and micropores on the β-TCP strut. The β-TCP foams exhibited high porosity (92 – 97%) and large pore size (200 - 750um) that resemble cancellous bone structure. |
| doi_str_mv | 10.4028/www.scientific.net/KEM.694.94 |
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A highly porous and interconnected porosity architecture of bone scaffold facilitates attachment and in-growth of new bone tissue. β-TCP foam, a porous 3-dimensional scaffold was fabricated by employing polymeric foam replica method in this study. Polyurethane (PU) foam was used as the sacrificial template, in which β-TCP slurry with powder to water ratio of 10g:10ml was coated on PU template and sintered to 1100, 1200, 1250 and 1300°C. Observation on architecture of the foam, macrostructure and microstructure of pores and surface topography of porous strut showed that sintering at 1250°C produced sufficient densification of grains and micropores on the β-TCP strut. 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The β-TCP foams exhibited high porosity (92 – 97%) and large pore size (200 - 750um) that resemble cancellous bone structure.</description><subject>Bones</subject><subject>Foams</subject><subject>Phosphates</subject><subject>Plastic foam</subject><subject>Polyurethane foam</subject><subject>Polyurethane resins</subject><subject>Porosity</subject><subject>Scaffolds</subject><issn>1013-9826</issn><issn>1662-9795</issn><issn>1662-9795</issn><isbn>3035710198</isbn><isbn>9783035710199</isbn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2016</creationdate><recordtype>article</recordtype><sourceid>BENPR</sourceid><recordid>eNqNkMtKxDAUhoMX8PoOBRHctCbNpc1CRMUbM6LguA5peuJEOu2YpAy-vZERFFeuzuJ8_38OH0LHBBcMl_XparUqgnHQR2edKXqIp5Prh0JIVki2gXaJEGUuK8k30R7FlFcEE1lvpQUmNJd1KXbQXghvGFNSE76LJs-uj-Bd_5oNNruEqPOZd0Z3xo2L7Gk-hOVcR8iejbZ26NrsJXyxT0P3MXqIc91DNoPFskvQAdq2ugtw-D330cvN9ezqLp8-3t5fXUxzwzBjORW1tNhCI6QtecOJoWVrmpo0QjRty7Qg1kojABpiS9FaTRk3mNMKDDHM0n10su5d-uF9hBDVwgUDXZeeGcagSF1yJivOcEKP_qBvw-j79J0ilSy5JEyIRJ2tKeOHEDxYtfRuof2HIlh9eVfJu_rxrpJ3lbyr5F1JlvLn63z0ug8RzPzXmX81fAI7IpK5</recordid><startdate>20160523</startdate><enddate>20160523</enddate><creator>Othman, Radzali</creator><creator>Wong, Wai Yee</creator><creator>Mohd Noor, Ahmad Fauzi</creator><general>Trans Tech Publications Ltd</general><scope>AAYXX</scope><scope>CITATION</scope><scope>7SR</scope><scope>8BQ</scope><scope>8FD</scope><scope>8FE</scope><scope>8FG</scope><scope>ABJCF</scope><scope>AFKRA</scope><scope>BENPR</scope><scope>BGLVJ</scope><scope>CCPQU</scope><scope>D1I</scope><scope>DWQXO</scope><scope>F28</scope><scope>FR3</scope><scope>HCIFZ</scope><scope>JG9</scope><scope>KB.</scope><scope>L6V</scope><scope>M7S</scope><scope>PDBOC</scope><scope>PHGZM</scope><scope>PHGZT</scope><scope>PKEHL</scope><scope>PQEST</scope><scope>PQGLB</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>PTHSS</scope></search><sort><creationdate>20160523</creationdate><title>Sintering of Beta-Tricalcium Phosphate Scaffold Using Polyurethane Template</title><author>Othman, Radzali ; 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| subjects | Bones Foams Phosphates Plastic foam Polyurethane foam Polyurethane resins Porosity Scaffolds |
| title | Sintering of Beta-Tricalcium Phosphate Scaffold Using Polyurethane Template |
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