Genomic and proteomic analysis of the inhibition of synthesis and secretion of aldosterone hormone induced by quinocetone in NCI-H295R cells

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Veröffentlicht in:	Toxicology (Amsterdam) 2016-03, Vol.350-352, p.1-14
Hauptverfasser:	Wang, Xu, Bai, Yijie, Cheng, Guyue, Ihsan, Awais, Zhu, Feng, Wang, Yulian, Tao, Yanfei, Chen, Dongmei, Dai, Menghong, Liu, Zhengli, Yuan, Zonghui
Format:	Artikel
Sprache:	eng
Schlagworte:	Adrenal Adrenal Cortex - drug effects Adrenal Cortex - pathology Adrenal Cortex Neoplasms - metabolism Aldosterone Aldosterone - biosynthesis Aldosterone - secretion Apoptosis - drug effects Cell Line, Tumor Dose-Response Relationship, Drug Emergency Gene Expression Regulation - drug effects Genes Genomics Genomics - methods Hormones Humans Mass Spectrometry - methods Microarray Analysis NCI-H295R cells Oxidative Stress - drug effects Pathways Proteins Proteomics Proteomics - methods Quinocetone Quinoxalines - administration & dosage Quinoxalines - toxicity Signal Transduction - drug effects Steroid 17-alpha-Hydroxylase - genetics Stresses Toxic Toxicology
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