A practical synthesis of novel chiral sulfoxide-nitrogen ligands
Novel chiral sulfoxide-nitrogen ligands which are derived from amino alcohols were developed. All of fourteen sulfoxide-nitrogen ligands can be synthesized by three steps without any chiral auxiliary. In addition, every step of the synthesis can be achieved in gram-scale by using the preparation of...
Gespeichert in:
Veröffentlicht in: | Tetrahedron 2016-05, Vol.72 (21), p.2671-2676 |
---|---|
Hauptverfasser: | , , , |
Format: | Artikel |
Sprache: | eng |
Schlagworte: | |
Online-Zugang: | Volltext |
Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
Zusammenfassung: | Novel chiral sulfoxide-nitrogen ligands which are derived from amino alcohols were developed. All of fourteen sulfoxide-nitrogen ligands can be synthesized by three steps without any chiral auxiliary. In addition, every step of the synthesis can be achieved in gram-scale by using the preparation of L9–L12 as examples. These sulfoxide-nitrogen ligands may be applicable to the asymmetric catalytic 1,3-dipolar cycloaddition of azomethine ylide with alkylidene malonate.
[Display omitted] |
---|---|
ISSN: | 0040-4020 1464-5416 |
DOI: | 10.1016/j.tet.2015.08.004 |