Rosuvastatin decreases testosterone levels but not sexual function in men with type 2 diabetes

Highlights • The serum levels of LDL are correlated with serum free testosterone levels. • Scores of the sexual health inventory for men are obviously and negatively correlated with free testosterone levels. • Rosuvastin reduces serum free testosterone, total cholesterol and LDL in patients with typ...

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Veröffentlicht in:	Diabetes research and clinical practice 2016-10, Vol.120, p.81-88
Hauptverfasser:	Hsieh, Ching Jung, Huang, Bin
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Cholesterol - blood Diabetes Diabetes Mellitus, Type 2 - blood Diabetes Mellitus, Type 2 - drug therapy Diabetes Mellitus, Type 2 - physiopathology Endocrinology & Metabolism Humans Hydroxymethylglutaryl-CoA Reductase Inhibitors - administration & dosage Hydroxymethylglutaryl-CoA Reductase Inhibitors - pharmacology Hypercholesterolemia Hypercholesterolemia - drug therapy Lipoproteins, HDL - blood Lipoproteins, LDL - blood Male Middle Aged Rosuvastatin Calcium - administration & dosage Rosuvastatin Calcium - pharmacology Sex Hormone-Binding Globulin - metabolism Sexual Behavior - drug effects Sexual dysfunction Sexual Dysfunction, Physiological - drug therapy Statin Testosterone Testosterone - blood Thyrotropin - blood Triglycerides - blood
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Beschreibung
Zusammenfassung:	Highlights • The serum levels of LDL are correlated with serum free testosterone levels. • Scores of the sexual health inventory for men are obviously and negatively correlated with free testosterone levels. • Rosuvastin reduces serum free testosterone, total cholesterol and LDL in patients with type 2 diabetes. • Rosuvastatin does not affect sexual function in men with type 2 diabetes.
ISSN:	0168-8227 1872-8227
DOI:	10.1016/j.diabres.2016.07.026