Evaluation of Clinicopathological Factors Related to the Prognosis of Gastric Neuroendocrine Carcinoma

Abstract Background Research on the clinicopathology and prognosis of gastric neuroendocrine carcinoma (GNEC) is rare, and a uniform standard for treatment has not been established. Therefore, we retrospectively analyzed the clinical data of 132 cases of GNEC to investigate the factors influencing p...

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Veröffentlicht in:European journal of surgical oncology 2016-10, Vol.42 (10), p.1464-1470
Hauptverfasser: Xie, Jian-Wei, Sun, Yu-Qin, Feng, Chang-Yin, Zheng, Chao-Hui, Li, Ping, Wang, Jia-Bin, Lin, Jian-Xian, Lu, Jun, Chen, Qi-Yue, Cao, Long-Long, Lin, Mi, Tu, Ru-Hong, Yang, Ying-Hong, Huang, Chang-Ming
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Sprache:eng
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Zusammenfassung:Abstract Background Research on the clinicopathology and prognosis of gastric neuroendocrine carcinoma (GNEC) is rare, and a uniform standard for treatment has not been established. Therefore, we retrospectively analyzed the clinical data of 132 cases of GNEC to investigate the factors influencing prognosis. Methods A total of 132 patients diagnosed with GNEC at Fujian Medical University Union Hospital from January 2006 to December 2013 were enrolled. This study was performed to analyze the factors related to patient prognosis. Results In total, 58 men and 74 women whose ages ranged from 38 to 83 years old (62 ± 10) were enrolled. The 1- and 3-year survival rates for these patients were 83.9% and 47.6%, respectively. Of these patients, 100 underwent radical resection, 22 underwent palliative resection, and 10 received chemotherapy alone. The median survival times following radical resection, palliative resection and chemotherapy alone were 48, 20 and 12 months, respectively (P
ISSN:0748-7983
1532-2157
DOI:10.1016/j.ejso.2016.08.004