Two Separate Colorectal Granular Cell Tumors

[...]malignant potential has been reported and can be either histologically and clinically malignant, or histologically benign and clinically malignant.4 Clinical features of malignancy include metastasis, large size, rapid growth, and invasion into adjacent tissues. Histologic diagnoses of malignancy are the presence of three or more of the following features: spindling of tumor cells, vesicular nuclei with large nucleoli, increased mitotic rate, a high nuclear-to-cytoplasmic ratio, pleomorphism, and necrosis.