In silico comparison of photons versus carbon ions in single fraction therapy of lung cancer

In silico comparison of photons versus carbon ions in single fraction therapy of lung cancer

Highlights • Using state of the art 4D dose calculation for carbon-ions. • Target coverage is the same for photons and carbon-ions with rescanning. • Carbon-ions deposit less dose in OAR than photons. • Patients with multiple targets or big target volumes benefit more from carbon-ions.

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Bibliographische Detailangaben
Veröffentlicht in:Physica medica 2016-09, Vol.32 (9), p.1118-1123
Hauptverfasser: Anderle, Kristjan, Stroom, Joep, Pimentel, Nuno, Greco, Carlo, Durante, Marco, Graeff, Christian
Format: Artikel
Sprache:eng
Schlagworte:
Carbon - chemistry
Dose-Response Relationship, Radiation
Humans
Imaging, Three-Dimensional - methods
Ions
Lung cancer
Lung Neoplasms - radiotherapy
Motion
Motion mitigation
Particle therapy
Photons
Radiology
Radiotherapy - methods
Radiotherapy Dosage
Radiotherapy Planning, Computer-Assisted
Radiotherapy, Image-Guided
Reproducibility of Results
Respiration
SDRT
Single fraction
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Beschreibung
Zusammenfassung:Highlights • Using state of the art 4D dose calculation for carbon-ions. • Target coverage is the same for photons and carbon-ions with rescanning. • Carbon-ions deposit less dose in OAR than photons. • Patients with multiple targets or big target volumes benefit more from carbon-ions.
ISSN:1120-1797
1724-191X
DOI:10.1016/j.ejmp.2016.08.014