Real-time investigation of cytochrome c release profiles in living neuronal cells undergoing amyloid beta oligomer-induced apoptosis
Intracellular Cyt c release profiles in living human neuroblastoma undergoing amyloid β oligomer (AβO)-induced apoptosis, as a model Alzheimer's disease-associated pathogenic molecule, were analysed in a real-time manner using plasmon resonance energy transfer (PRET)-based spectroscopy.
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| Veröffentlicht in: | Nanoscale 2015-06, Vol.7 (23), p.10340-10343 |
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| container_end_page | 10343 |
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| container_issue | 23 |
| container_start_page | 10340 |
| container_title | Nanoscale |
| container_volume | 7 |
| creator | Lee, Jae Young Park, Younggeun Pun, San Lee, Sung Sik Lo, Joe F Lee, Luke P |
| description | Intracellular Cyt c release profiles in living human neuroblastoma undergoing amyloid β oligomer (AβO)-induced apoptosis, as a model Alzheimer's disease-associated pathogenic molecule, were analysed in a real-time manner using plasmon resonance energy transfer (PRET)-based spectroscopy. |
| doi_str_mv | 10.1039/c5nr02390d |
| format | Article |
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| fulltext | fulltext |
| identifier | ISSN: 2040-3364 |
| ispartof | Nanoscale, 2015-06, Vol.7 (23), p.10340-10343 |
| issn | 2040-3364 2040-3372 |
| language | eng |
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| source | MEDLINE; Royal Society Of Chemistry Journals 2008-; Alma/SFX Local Collection |
| subjects | Amyloid beta-Peptides - pharmacology Apoptosis Apoptosis - drug effects Apoptosis - physiology Cell Line Computer Systems Cytochromes c - metabolism Energy transfer Fluorescence Resonance Energy Transfer - methods Human Humans Molecular Imaging - methods Nanostructure Neurons - cytology Neurons - drug effects Neurons - secretion Oligomers Plasmons Real time Spectroscopy Surface Plasmon Resonance - methods |
| title | Real-time investigation of cytochrome c release profiles in living neuronal cells undergoing amyloid beta oligomer-induced apoptosis |
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