A randomized double-blind controlled trial comparing two regimens of vitamin D supplementation in preterm neonates

Objective: To compare the efficacy of 400 vs 1000 IU oral vitamin D supplementation in preterm neonates of 27 to 34 weeks gestation. Methods: This double-blind randomized controlled trial allocated preterm babies to receive either 400 or 1000 IU of vitamin D 3 ( n =60 in each group). Primary outcome...

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Veröffentlicht in:	Journal of perinatology 2016-09, Vol.36 (9), p.763-767
Hauptverfasser:	Tergestina, M, Rebekah, G, Job, V, Simon, A, Thomas, N
Format:	Artikel
Sprache:	eng
Schlagworte:	631/443/63 631/443/810 692/699/2743/316 692/700/1720 706/134 82/51 82/56 Breastfeeding & lactation Calciferol Calcium - blood Cholecalciferol - administration & dosage Cholecalciferol - blood Clinical trials Dietary Supplements Dose-response relationship Dose-Response Relationship, Drug Double-Blind Method Double-blind studies Drug dosages Female Gestational Age Health aspects Humans India Infant, Newborn Male Medical schools Medicine Medicine & Public Health Neonatal care Neonates Newborn babies original-article Pediatric Surgery Pediatrics Phosphatase Premature babies Premature infants Prevention Tertiary Care Centers Toxicity Vitamin D Vitamin D deficiency Vitamin D Deficiency - blood Vitamin D Deficiency - drug therapy Vitamin D3
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Beschreibung
Zusammenfassung:	Objective: To compare the efficacy of 400 vs 1000 IU oral vitamin D supplementation in preterm neonates of 27 to 34 weeks gestation. Methods: This double-blind randomized controlled trial allocated preterm babies to receive either 400 or 1000 IU of vitamin D 3 ( n =60 in each group). Primary outcome was prevalence of vitamin D insufficiency (serum vitamin D levels
ISSN:	0743-8346 1476-5543
DOI:	10.1038/jp.2016.70