Testicular prostheses in children: is earlier better?
Summary Introduction The absence of a testis occurs for various reasons in children, but testicular prosthesis implantation in children is uncommon. The optimal time for prosthesis placement is still unclear, and its complication rate has been poorly studied in children. Objective The aim of this st...
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| Veröffentlicht in: | Journal of pediatric urology 2016-08, Vol.12 (4), p.237.e1-237.e6 |
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| creator | Peycelon, M Rossignol, G Muller, C.O Carricaburu, E Philippe-Chomette, P Paye-Jaouen, A El Ghoneimi, A |
| description | Summary Introduction The absence of a testis occurs for various reasons in children, but testicular prosthesis implantation in children is uncommon. The optimal time for prosthesis placement is still unclear, and its complication rate has been poorly studied in children. Objective The aim of this study was to determine the risk factors of complications in cases of testicular prosthesis implantation in children. Study design A monocentric, retrospective review was performed of children implanted with a testicular prosthesis between 2008 and 2014. All implantations were performed through an inguinal incision with a standardized procedure. Children were divided into two groups depending on the interval after orchiectomy: (A) early implantation (delay between surgeries |
| doi_str_mv | 10.1016/j.jpurol.2016.04.022 |
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| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_1817053318</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S147751311630050X</els_id><sourcerecordid>1817053318</sourcerecordid><originalsourceid>FETCH-LOGICAL-c417t-9781a4a4a8d4d0939b479e8ae2d44fe9709ff71525b51ac287235929cf6a62013</originalsourceid><addsrcrecordid>eNqFkUtLxDAUhYMozjj6D0S6dNOaV5vEhSKDLxBcqOAuZNJbTM20Y9IK8-_NMOrCjWSRBM6995zvInRMcEEwqc7aol2NofcFTb8C8wJTuoOmRAqWc6nkbnpzIfKSMDJBBzG2GDOBqdpHEypoxXGJp6h8hjg4O3oTslXo4_AGEWLmusy-OV8H6M4zFzMwwTsI2QKGAcLlIdprjI9w9H3P0MvN9fP8Ln94vL2fXz3klhMx5EpIYng6suY1VkwtuFAgDdCa8waUwKppBClpuSiJsVQKykpFlW0qU6VYbIZOt32TtY8xOdVLFy14bzrox6iJJAKXjBGZpHwrtSlFDNDoVXBLE9aaYL0Bplu9BaY3wDTmOgFLZSffE8bFEurfoh9CSXCxFUDK-ZkY6GgddBZqF8AOuu7dfxP-NrDedc4a_w5riG0_hi4x1ERHqrF-2ixtszNSMZwMvLIvd2SRlg</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1817053318</pqid></control><display><type>article</type><title>Testicular prostheses in children: is earlier better?</title><source>MEDLINE</source><source>Elsevier ScienceDirect Journals Complete</source><creator>Peycelon, M ; Rossignol, G ; Muller, C.O ; Carricaburu, E ; Philippe-Chomette, P ; Paye-Jaouen, A ; El Ghoneimi, A</creator><creatorcontrib>Peycelon, M ; Rossignol, G ; Muller, C.O ; Carricaburu, E ; Philippe-Chomette, P ; Paye-Jaouen, A ; El Ghoneimi, A</creatorcontrib><description>Summary Introduction The absence of a testis occurs for various reasons in children, but testicular prosthesis implantation in children is uncommon. The optimal time for prosthesis placement is still unclear, and its complication rate has been poorly studied in children. Objective The aim of this study was to determine the risk factors of complications in cases of testicular prosthesis implantation in children. Study design A monocentric, retrospective review was performed of children implanted with a testicular prosthesis between 2008 and 2014. All implantations were performed through an inguinal incision with a standardized procedure. Children were divided into two groups depending on the interval after orchiectomy: (A) early implantation (delay between surgeries <1 year); and (B) delayed surgeries (delay ≥1 year). Statistical analysis was performed with Student and Fisher tests. Results Twenty-six patients (A, 15; B, 11) had a total of 38 testicular prostheses placements. Mean follow-up was 36.2 months. First surgery was performed at the mean age of 11.8 years (range 0-17.9) (A, 14.1; B, 8.1; P =0.01) and testicular prosthesis implantation at the mean age of 14.7 years (range 9-18) (A, 14.3; B, 14.6) with a mean delay of 36.1 months (A, 1.3; B, 80.3). Indications were mainly spermatic cord torsion (27%), bilateral anorchia (27%), and testicular atrophy after cryptorchidism surgery (19.2%). Complications (10.5%) included two cases of extrusion, one infection and one migration. Patient 1 had a history of acute lymphoblastic leukemia with testicle relapse 2 years after induction therapy. High-dose chemotherapy, total body irradiation and bilateral orchiectomies were performed, and bilateral prostheses were implanted 12 years after the end of chemotherapy. Complications happened 85 days after surgery. Patient 2 was followed-up for a proximal hypospadias. The tunica vaginalis flap, which was used during a redo urethroplasty, lead to testicular atrophy. Thirteen years after the last penile surgery, a testicular prosthesis was placed through an inguinal incision, and extrusion occurred 203 days after surgery. Bacterial cultures of the prostheses were sterile and histological review showed no sign of granuloma or graft rejection. The complication rate was significantly higher if the delay between the two surgeries exceeded 1 year ( P =0.01). Indications of orchiectomy, prior scrotal incision, and prosthesis size were not risk factors. Conclusions Testicular prosthesis implantation was relatively safe in a pediatric cohort. The complication rate was significantly higher if the delay between the orchiectomy and the prosthetic placement exceeded 1 year. These results suggest that reducing the delay between orchiectomy and prosthesis implantation may lead to fewer complications.</description><identifier>ISSN: 1477-5131</identifier><identifier>EISSN: 1873-4898</identifier><identifier>DOI: 10.1016/j.jpurol.2016.04.022</identifier><identifier>PMID: 27264050</identifier><language>eng</language><publisher>England: Elsevier Ltd</publisher><subject>Adolescent ; Anorchia ; Child ; Child, Preschool ; Gonadal Dysgenesis, 46,XY - surgery ; Humans ; Infant ; Male ; Orchiectomy ; Pediatrics ; Postoperative complications ; Postoperative Complications - epidemiology ; Postoperative Complications - etiology ; Prostheses and Implants ; Prosthesis implantation ; Prosthesis Implantation - adverse effects ; Retrospective Studies ; Risk Factors ; Spermatic cord torsion ; Spermatic Cord Torsion - surgery ; Testis - abnormalities ; Testis - surgery ; Urology</subject><ispartof>Journal of pediatric urology, 2016-08, Vol.12 (4), p.237.e1-237.e6</ispartof><rights>2016 Journal of Pediatric Urology Company</rights><rights>Copyright © 2016 Journal of Pediatric Urology Company. Published by Elsevier Ltd. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c417t-9781a4a4a8d4d0939b479e8ae2d44fe9709ff71525b51ac287235929cf6a62013</citedby><cites>FETCH-LOGICAL-c417t-9781a4a4a8d4d0939b479e8ae2d44fe9709ff71525b51ac287235929cf6a62013</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S147751311630050X$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3537,27901,27902,65306</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/27264050$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Peycelon, M</creatorcontrib><creatorcontrib>Rossignol, G</creatorcontrib><creatorcontrib>Muller, C.O</creatorcontrib><creatorcontrib>Carricaburu, E</creatorcontrib><creatorcontrib>Philippe-Chomette, P</creatorcontrib><creatorcontrib>Paye-Jaouen, A</creatorcontrib><creatorcontrib>El Ghoneimi, A</creatorcontrib><title>Testicular prostheses in children: is earlier better?</title><title>Journal of pediatric urology</title><addtitle>J Pediatr Urol</addtitle><description>Summary Introduction The absence of a testis occurs for various reasons in children, but testicular prosthesis implantation in children is uncommon. The optimal time for prosthesis placement is still unclear, and its complication rate has been poorly studied in children. Objective The aim of this study was to determine the risk factors of complications in cases of testicular prosthesis implantation in children. Study design A monocentric, retrospective review was performed of children implanted with a testicular prosthesis between 2008 and 2014. All implantations were performed through an inguinal incision with a standardized procedure. Children were divided into two groups depending on the interval after orchiectomy: (A) early implantation (delay between surgeries <1 year); and (B) delayed surgeries (delay ≥1 year). Statistical analysis was performed with Student and Fisher tests. Results Twenty-six patients (A, 15; B, 11) had a total of 38 testicular prostheses placements. Mean follow-up was 36.2 months. First surgery was performed at the mean age of 11.8 years (range 0-17.9) (A, 14.1; B, 8.1; P =0.01) and testicular prosthesis implantation at the mean age of 14.7 years (range 9-18) (A, 14.3; B, 14.6) with a mean delay of 36.1 months (A, 1.3; B, 80.3). Indications were mainly spermatic cord torsion (27%), bilateral anorchia (27%), and testicular atrophy after cryptorchidism surgery (19.2%). Complications (10.5%) included two cases of extrusion, one infection and one migration. Patient 1 had a history of acute lymphoblastic leukemia with testicle relapse 2 years after induction therapy. High-dose chemotherapy, total body irradiation and bilateral orchiectomies were performed, and bilateral prostheses were implanted 12 years after the end of chemotherapy. Complications happened 85 days after surgery. Patient 2 was followed-up for a proximal hypospadias. The tunica vaginalis flap, which was used during a redo urethroplasty, lead to testicular atrophy. Thirteen years after the last penile surgery, a testicular prosthesis was placed through an inguinal incision, and extrusion occurred 203 days after surgery. Bacterial cultures of the prostheses were sterile and histological review showed no sign of granuloma or graft rejection. The complication rate was significantly higher if the delay between the two surgeries exceeded 1 year ( P =0.01). Indications of orchiectomy, prior scrotal incision, and prosthesis size were not risk factors. Conclusions Testicular prosthesis implantation was relatively safe in a pediatric cohort. The complication rate was significantly higher if the delay between the orchiectomy and the prosthetic placement exceeded 1 year. These results suggest that reducing the delay between orchiectomy and prosthesis implantation may lead to fewer complications.</description><subject>Adolescent</subject><subject>Anorchia</subject><subject>Child</subject><subject>Child, Preschool</subject><subject>Gonadal Dysgenesis, 46,XY - surgery</subject><subject>Humans</subject><subject>Infant</subject><subject>Male</subject><subject>Orchiectomy</subject><subject>Pediatrics</subject><subject>Postoperative complications</subject><subject>Postoperative Complications - epidemiology</subject><subject>Postoperative Complications - etiology</subject><subject>Prostheses and Implants</subject><subject>Prosthesis implantation</subject><subject>Prosthesis Implantation - adverse effects</subject><subject>Retrospective Studies</subject><subject>Risk Factors</subject><subject>Spermatic cord torsion</subject><subject>Spermatic Cord Torsion - surgery</subject><subject>Testis - abnormalities</subject><subject>Testis - surgery</subject><subject>Urology</subject><issn>1477-5131</issn><issn>1873-4898</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2016</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkUtLxDAUhYMozjj6D0S6dNOaV5vEhSKDLxBcqOAuZNJbTM20Y9IK8-_NMOrCjWSRBM6995zvInRMcEEwqc7aol2NofcFTb8C8wJTuoOmRAqWc6nkbnpzIfKSMDJBBzG2GDOBqdpHEypoxXGJp6h8hjg4O3oTslXo4_AGEWLmusy-OV8H6M4zFzMwwTsI2QKGAcLlIdprjI9w9H3P0MvN9fP8Ln94vL2fXz3klhMx5EpIYng6suY1VkwtuFAgDdCa8waUwKppBClpuSiJsVQKykpFlW0qU6VYbIZOt32TtY8xOdVLFy14bzrox6iJJAKXjBGZpHwrtSlFDNDoVXBLE9aaYL0Bplu9BaY3wDTmOgFLZSffE8bFEurfoh9CSXCxFUDK-ZkY6GgddBZqF8AOuu7dfxP-NrDedc4a_w5riG0_hi4x1ERHqrF-2ixtszNSMZwMvLIvd2SRlg</recordid><startdate>20160801</startdate><enddate>20160801</enddate><creator>Peycelon, M</creator><creator>Rossignol, G</creator><creator>Muller, C.O</creator><creator>Carricaburu, E</creator><creator>Philippe-Chomette, P</creator><creator>Paye-Jaouen, A</creator><creator>El Ghoneimi, A</creator><general>Elsevier Ltd</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20160801</creationdate><title>Testicular prostheses in children: is earlier better?</title><author>Peycelon, M ; Rossignol, G ; Muller, C.O ; Carricaburu, E ; Philippe-Chomette, P ; Paye-Jaouen, A ; El Ghoneimi, A</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c417t-9781a4a4a8d4d0939b479e8ae2d44fe9709ff71525b51ac287235929cf6a62013</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2016</creationdate><topic>Adolescent</topic><topic>Anorchia</topic><topic>Child</topic><topic>Child, Preschool</topic><topic>Gonadal Dysgenesis, 46,XY - surgery</topic><topic>Humans</topic><topic>Infant</topic><topic>Male</topic><topic>Orchiectomy</topic><topic>Pediatrics</topic><topic>Postoperative complications</topic><topic>Postoperative Complications - epidemiology</topic><topic>Postoperative Complications - etiology</topic><topic>Prostheses and Implants</topic><topic>Prosthesis implantation</topic><topic>Prosthesis Implantation - adverse effects</topic><topic>Retrospective Studies</topic><topic>Risk Factors</topic><topic>Spermatic cord torsion</topic><topic>Spermatic Cord Torsion - surgery</topic><topic>Testis - abnormalities</topic><topic>Testis - surgery</topic><topic>Urology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Peycelon, M</creatorcontrib><creatorcontrib>Rossignol, G</creatorcontrib><creatorcontrib>Muller, C.O</creatorcontrib><creatorcontrib>Carricaburu, E</creatorcontrib><creatorcontrib>Philippe-Chomette, P</creatorcontrib><creatorcontrib>Paye-Jaouen, A</creatorcontrib><creatorcontrib>El Ghoneimi, A</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of pediatric urology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Peycelon, M</au><au>Rossignol, G</au><au>Muller, C.O</au><au>Carricaburu, E</au><au>Philippe-Chomette, P</au><au>Paye-Jaouen, A</au><au>El Ghoneimi, A</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Testicular prostheses in children: is earlier better?</atitle><jtitle>Journal of pediatric urology</jtitle><addtitle>J Pediatr Urol</addtitle><date>2016-08-01</date><risdate>2016</risdate><volume>12</volume><issue>4</issue><spage>237.e1</spage><epage>237.e6</epage><pages>237.e1-237.e6</pages><issn>1477-5131</issn><eissn>1873-4898</eissn><abstract>Summary Introduction The absence of a testis occurs for various reasons in children, but testicular prosthesis implantation in children is uncommon. The optimal time for prosthesis placement is still unclear, and its complication rate has been poorly studied in children. Objective The aim of this study was to determine the risk factors of complications in cases of testicular prosthesis implantation in children. Study design A monocentric, retrospective review was performed of children implanted with a testicular prosthesis between 2008 and 2014. All implantations were performed through an inguinal incision with a standardized procedure. Children were divided into two groups depending on the interval after orchiectomy: (A) early implantation (delay between surgeries <1 year); and (B) delayed surgeries (delay ≥1 year). Statistical analysis was performed with Student and Fisher tests. Results Twenty-six patients (A, 15; B, 11) had a total of 38 testicular prostheses placements. Mean follow-up was 36.2 months. First surgery was performed at the mean age of 11.8 years (range 0-17.9) (A, 14.1; B, 8.1; P =0.01) and testicular prosthesis implantation at the mean age of 14.7 years (range 9-18) (A, 14.3; B, 14.6) with a mean delay of 36.1 months (A, 1.3; B, 80.3). Indications were mainly spermatic cord torsion (27%), bilateral anorchia (27%), and testicular atrophy after cryptorchidism surgery (19.2%). Complications (10.5%) included two cases of extrusion, one infection and one migration. Patient 1 had a history of acute lymphoblastic leukemia with testicle relapse 2 years after induction therapy. High-dose chemotherapy, total body irradiation and bilateral orchiectomies were performed, and bilateral prostheses were implanted 12 years after the end of chemotherapy. Complications happened 85 days after surgery. Patient 2 was followed-up for a proximal hypospadias. The tunica vaginalis flap, which was used during a redo urethroplasty, lead to testicular atrophy. Thirteen years after the last penile surgery, a testicular prosthesis was placed through an inguinal incision, and extrusion occurred 203 days after surgery. Bacterial cultures of the prostheses were sterile and histological review showed no sign of granuloma or graft rejection. The complication rate was significantly higher if the delay between the two surgeries exceeded 1 year ( P =0.01). Indications of orchiectomy, prior scrotal incision, and prosthesis size were not risk factors. Conclusions Testicular prosthesis implantation was relatively safe in a pediatric cohort. The complication rate was significantly higher if the delay between the orchiectomy and the prosthetic placement exceeded 1 year. These results suggest that reducing the delay between orchiectomy and prosthesis implantation may lead to fewer complications.</abstract><cop>England</cop><pub>Elsevier Ltd</pub><pmid>27264050</pmid><doi>10.1016/j.jpurol.2016.04.022</doi></addata></record> |
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| subjects | Adolescent Anorchia Child Child, Preschool Gonadal Dysgenesis, 46,XY - surgery Humans Infant Male Orchiectomy Pediatrics Postoperative complications Postoperative Complications - epidemiology Postoperative Complications - etiology Prostheses and Implants Prosthesis implantation Prosthesis Implantation - adverse effects Retrospective Studies Risk Factors Spermatic cord torsion Spermatic Cord Torsion - surgery Testis - abnormalities Testis - surgery Urology |
| title | Testicular prostheses in children: is earlier better? |
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