A modified two-stage markov clustering algorithm for large and sparse networks

Highlights • A fast and memory efficient, two-stage Markov clustering algorithm is proposed. • The algorithm is designed for the analysis of large and sparse graphs. • The algorithm was validated using real and synthetic protein sequence data. • It can accurately process a million-node BLAST similar...

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Veröffentlicht in:Computer methods and programs in biomedicine 2016-10, Vol.135, p.15-26
Hauptverfasser: Szilágyi, László, Szilágyi, Sándor M
Format: Artikel
Sprache:eng
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Zusammenfassung:Highlights • A fast and memory efficient, two-stage Markov clustering algorithm is proposed. • The algorithm is designed for the analysis of large and sparse graphs. • The algorithm was validated using real and synthetic protein sequence data. • It can accurately process a million-node BLAST similarity network in 100 minutes.
ISSN:0169-2607
1872-7565
DOI:10.1016/j.cmpb.2016.07.007