Rapid Assembly of Heterogeneous 3D Cell Microenvironments in a Microgel Array

Heterogeneous 3D cell microenvironment arrays are rapidly assembled by combining surface‐wettability‐guided assembly and microdroplet‐array‐based operations. This approach enables precise control over individual shapes, sizes, chemical concentrations, cell density, and 3D spatial distribution of mul...

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Veröffentlicht in:Advanced materials (Weinheim) 2016-05, Vol.28 (18), p.3543-3548
Hauptverfasser: Li, Yiwei, Chen, Pu, Wang, Yachao, Yan, Shuangqian, Feng, Xiaojun, Du, Wei, Koehler, Stephan A., Demirci, Utkan, Liu, Bi-Feng
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Sprache:eng
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Zusammenfassung:Heterogeneous 3D cell microenvironment arrays are rapidly assembled by combining surface‐wettability‐guided assembly and microdroplet‐array‐based operations. This approach enables precise control over individual shapes, sizes, chemical concentrations, cell density, and 3D spatial distribution of multiple components. This technique provides a cost‐effective solution to meet the increasing demand of stem cell research, tissue engineering, and drug screening.
ISSN:0935-9648
1521-4095
DOI:10.1002/adma.201600247