Analyte migration electrospray ionization for rapid analysis of complex samples with small volume using mass spectrometry

Analyte migration electrospray ionization for rapid analysis of complex samples with small volume using mass spectrometry

Complex biological matrices can be effectively removed in the analyte migration process because of their weak solubility in organic solvents. This technique offers other potential advantages, including high-sensitivity and the capability of performing a direct analysis of the components and their me...

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Veröffentlicht in:Analyst (London) 2014-11, Vol.139 (22), p.5678-5681
Hauptverfasser: Wang, Qian, Zhong, Hanbin, Zheng, Yajun, Zhang, Sichun, Liu, Xiaoning, Zhang, Xinrong, Zhang, Xiaoling, Zhang, Zhiping
Format: Artikel
Sprache:eng
Schlagworte:
Analytical chemistry
Ionization
Mass spectrometry
Metabolites
Migration
Raw
Solubility
Solvents
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Beschreibung
Zusammenfassung:Complex biological matrices can be effectively removed in the analyte migration process because of their weak solubility in organic solvents. This technique offers other potential advantages, including high-sensitivity and the capability of performing a direct analysis of the components and their metabolites in small-volume raw samples without any pretreatment.
ISSN:0003-2654
1364-5528
DOI:10.1039/c4an01397b