Interleukin (IL)-8 immunoreactivity of injured axons and surrounding oligodendrocytes in traumatic head injury

Interleukin (IL)-8 immunoreactivity of injured axons and surrounding oligodendrocytes in traumatic head injury

Highlights • We examined IL-8 immunoreactivity in the corpus callosum of deceased patients with traumatic brain injury. • IL-8 immunoreactivity was detected in 9 of the 44 cases of traumatic brain injury. • The survival time after traumatic brain injury of IL-8 immunoreactive cases was 3 to 24 days....

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Forensic science international 2016-06, Vol.263, p.48-54
Hauptverfasser: Hayashi, Takahito, Ago, Kazutoshi, Nakamae, Takuma, Higo, Eri, Ogata, Mamoru
Format: Artikel
Sprache:eng
Schlagworte:
Adolescent
Adult
Age
Aged
Aged, 80 and over
Amyloid beta-Protein Precursor - analysis
Axons
Axons - immunology
Axons - metabolism
Beta-amyloid precursor protein (AβPP)
Biomarkers - metabolism
Case-Control Studies
Central nervous system
Child
Corpus Callosum - immunology
Corpus Callosum - metabolism
Cytokines
Diagnostic systems
Female
Forensic Pathology
Forensic sciences
Head injuries
Head Injuries, Closed - metabolism
Head Injuries, Closed - pathology
Heart attacks
Hemorrhage
Humans
Immunohistochemistry
Injuries
Interleukin
Interleukin (IL)-8
Interleukin-8 - metabolism
Legal medicine
Male
Middle Aged
Oligodendroglia - immunology
Oligodendroglia - metabolism
Pathology
Patients
Postmortem diagnosis
Proteins
Remyelination
Strangulation
Traumatic axonal injury
Tumor necrosis factor-TNF
Young Adult
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:Highlights • We examined IL-8 immunoreactivity in the corpus callosum of deceased patients with traumatic brain injury. • IL-8 immunoreactivity was detected in 9 of the 44 cases of traumatic brain injury. • The survival time after traumatic brain injury of IL-8 immunoreactive cases was 3 to 24 days. • IL-8 was also detected in oligodendrocytes surrounding the injured axons.
ISSN:0379-0738
1872-6283
DOI:10.1016/j.forsciint.2016.03.055