Regional and sex-related differences in modulating effects of female sex steroids on ecto-5′-nucleotidase expression in the rat cerebral cortex and hippocampus

Highlights • Hippocampus of male rats exerts the highest basal eN activity. • Treatments with the sex steroids do not alter eN in the male cortex and hippocampus. • In the OVX females, the main effects of treatments with the sex steroids were alterations in eN activity. • Steroids induce different e...

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Veröffentlicht in:General and comparative endocrinology 2016-09, Vol.235, p.100-107
Hauptverfasser: Mitrović, Nataša, Guševac, Ivana, Drakulić, Dunja, Stanojlović, Miloš, Zlatković, Jelena, Sévigny, Jean, Horvat, Anica, Nedeljković, Nadežda, Grković, Ivana
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Sprache:eng
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Zusammenfassung:Highlights • Hippocampus of male rats exerts the highest basal eN activity. • Treatments with the sex steroids do not alter eN in the male cortex and hippocampus. • In the OVX females, the main effects of treatments with the sex steroids were alterations in eN activity. • Steroids induce different effects at the eN activity in the cortex and hippocampus of OVX rats.
ISSN:0016-6480
1095-6840
DOI:10.1016/j.ygcen.2016.06.018