Combretins A and B, New Cycloartane-Type Triterpenes from Combretum fragrans

The phytochemical studies on the leaves of the traditionally used medicinal plant Combretum fragrans F. Hoffm (Combretaceae) from Cameroon have led to the isolation of combretins A and B (1 and 2, resp.), two new cycloartane‐type triterpenes from the AcOEt‐soluble subfraction along with β‐sitosterol (3), oleanolic acid (4), ursolic acid (5), and pratensein (6). The compounds 4 – 6 are reported for the first time from this species. The structures of the new triterpenes were elucidated by spectroscopic techniques including 1H‐ and 13C‐NMR (DEPT), and 2D‐NMR experiments. Combretins A and B, New Cycloartane‐Type Triterpenes from Combretum fragrans A. Dawe*, G. D. W. F. Kapche, J. J. K. Bankeu, Y. Fawai, M. S. Ali, B. T. Ngadjui