Can cross-talk occur in human myelinated nerve fibers?

ABSTRACT Introduction: The possibility that impulse cross‐talk can occur between myelinated human nerve fibers was explored. Methods: Instances of impulse conduction without decrement were found, and published recordings of compound action potentials of functionally homogeneous fibers were scrutinized. Results: Both analytical approaches yielded results consistent with cross‐talk occurring in some nerves after electrical stimulation. Conclusions: The possible ionic current paths in and out of neighboring fibers, which could be responsible for the phenomenon, have been considered in the light of seminal work on unmyelinated single axons. Muscle Nerve 54: 361–365, 2016