Multifocal Versus Solitary Papillary Thyroid Carcinoma

Background Papillary Thyroid Carcinoma (PTC) which accounts for >85 % of all thyroid cancers in iodine-rich areas, appears either as a single tumor or as two or more, neoplastic foci within the thyroid gland (Multifocal PTC). We present the comparative results between solitary and MFC PTC. Materi...

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Veröffentlicht in:World journal of surgery 2016-09, Vol.40 (9), p.2139-2143
Hauptverfasser: Kiriakopoulos, Andreas, Petralias, Athanassios, Linos, Dimitrios
Format: Artikel
Sprache:eng
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Zusammenfassung:Background Papillary Thyroid Carcinoma (PTC) which accounts for >85 % of all thyroid cancers in iodine-rich areas, appears either as a single tumor or as two or more, neoplastic foci within the thyroid gland (Multifocal PTC). We present the comparative results between solitary and MFC PTC. Materials and methods Demographics, tumor characteristics (size, laterality, foci number, histologic subtype) and TNM staging were compared between solitary and MFPTC patients. The presence of lymphocytic or Hashimoto’s thyroditis was also recorded. Results From January 2008 to December 2012, among 647 PTC patients, 241(37.2 %) had MFPTC 177 females (73.4 %) and 64 males (26.6 %), mean age 48.5 years (range 12–87). Mean number of tumor foci was 3.3 (range 2–26). MFPTC patients presented with more advanced T stage (28.2 vs. 18.7 %, p  = 0.01) and more LN metastases (28.6 vs. 15.5 %, p  
ISSN:0364-2313
1432-2323
DOI:10.1007/s00268-016-3628-5