Boosting Slow Oscillatory Activity Using tDCS during Early Nocturnal Slow Wave Sleep Does Not Improve Memory Consolidation in Healthy Older Adults

Highlights • Night-time so-tDCS enhanced slow wave and spindle activity following stimulation. • But so-tDCS decreased sleep stage 4 in older healthy subjects. • So-tDCS did not result in an improvement of declarative memory. • Future studies should focus on age-adjusted stimulation protocols....

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Veröffentlicht in:	Brain stimulation 2016-09, Vol.9 (5), p.730-739
Hauptverfasser:	Paßmann, Sven, Külzow, Nadine, Ladenbauer, Julia, Antonenko, Daria, Grittner, Ulrike, Tamm, Sascha, Flöel, Agnes
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Aged, 80 and over Consolidation Cross-Over Studies Declarative memory Female Frontal Lobe - physiology Healthy Volunteers Hippocampus - physiology Humans Male Memory Consolidation - physiology Middle Aged Neurology Older subjects Single-Blind Method Sleep - physiology Transcranial Direct Current Stimulation - methods Transcranial slow oscillating stimulation Treatment Outcome Visuo-spatial task
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Zusammenfassung:	Highlights • Night-time so-tDCS enhanced slow wave and spindle activity following stimulation. • But so-tDCS decreased sleep stage 4 in older healthy subjects. • So-tDCS did not result in an improvement of declarative memory. • Future studies should focus on age-adjusted stimulation protocols.
ISSN:	1935-861X 1876-4754
DOI:	10.1016/j.brs.2016.04.016