Towards Single-Step Biofabrication of Organs on a Chip via 3D Printing

Organ-on-a-chip engineering employs microfabrication of living tissues within microscale fluid channels to create constructs that closely mimic human organs. With the advent of 3D printing, we predict that single-step fabrication of these devices will enable rapid design and cost-effective iteration...

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Veröffentlicht in:	Trends in biotechnology (Regular ed.) 2016-09, Vol.34 (9), p.685-688
Hauptverfasser:	Knowlton, Stephanie, Yenilmez, Bekir, Tasoglu, Savas
Format:	Artikel
Sprache:	eng
Schlagworte:	3-D printers 3D printing Animals Biocompatibility biofabrication bioprinting Bioprinting - instrumentation Bioprinting - methods Cell Culture Techniques - instrumentation Cell Culture Techniques - methods Design Fabrication Humans Hydrogels Internal Medicine Lab-On-A-Chip Devices Lasers Mechanical properties microfluidics organ-on-a-chip Printing, Three-Dimensional - instrumentation Stem cells Tissue engineering Tissue Engineering - instrumentation Tissue Engineering - methods
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Beschreibung
Zusammenfassung:	Organ-on-a-chip engineering employs microfabrication of living tissues within microscale fluid channels to create constructs that closely mimic human organs. With the advent of 3D printing, we predict that single-step fabrication of these devices will enable rapid design and cost-effective iterations in the development stage, facilitating rapid innovation in this field.
ISSN:	0167-7799 1879-3096
DOI:	10.1016/j.tibtech.2016.06.005