Twelve-month and sixty-month outcomes of noncultured cellular grafting for vitiligo

Background Noncultured cellular grafting is a known surgical technique for vitiligo. Objective This study evaluated our center's 12-month repigmentation outcome and its maintenance up to 60 months, factors influencing repigmentation and safety data. Methods Clinicoepidemiologic and repigmentati...

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Veröffentlicht in:Journal of the American Academy of Dermatology 2016-09, Vol.75 (3), p.564-571
Hauptverfasser: Gan, Emily Yiping, MBBS(Honors), MRCP(UK), MMed(Int Med), Kong, Yan Ling, MBBS, Tan, Wei Ding, MSc (Statistics), Thng, Steven T., MBBS, MRCP (UK), FRCP (Edin), Goh, Boon Kee, BSc(Hons), MBChB(UK), MRCP(UK), FRCP(Edin)
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Sprache:eng
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Zusammenfassung:Background Noncultured cellular grafting is a known surgical technique for vitiligo. Objective This study evaluated our center's 12-month repigmentation outcome and its maintenance up to 60 months, factors influencing repigmentation and safety data. Methods Clinicoepidemiologic and repigmentation data were reviewed for patients with vitiligo who had undergone noncultured cellular grafting from March 2006 to December 2012 at the National Skin Center, Singapore. Results All 177 patients who received noncultured cellular grafting during the study period were included. For those with available data, good to excellent repigmentation was present in 83% at 60 months. At 12 months, 88% of patients (n = 52) with segmental vitiligo achieved good to excellent repigmentation compared with 71% (n = 55) with nonsegmental vitiligo ( P  
ISSN:0190-9622
1097-6787
DOI:10.1016/j.jaad.2016.04.007