Prevalence and drug resistance pattern of MDR TB in retreatment cases of Punjab, Pakistan

To determine the prevalence and resistance pattern of multidrug-resistant tuberculosis. This cross-sectional study was carried out from January 2010 to June 2014 in nine tertiary care hospitals implementing programmatic management of drug-resistant tuberculosis in Punjab, and comprised retreatment t...

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Veröffentlicht in:	Journal of the Pakistan Medical Association 2016-08, Vol.66 (8), p.989-993
Hauptverfasser:	Akhtar, Abdul Majeed, Arif, Muhammad Awais, Kanwal, Shamsa, Majeed, Sadia
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Analysis Antitubercular agents Antitubercular Agents - therapeutic use Child Child, Preschool Cross-Sectional Studies Drug Resistance, Multiple, Bacterial Drug therapy Ethionamide Female Fluoroquinolones Humans Infant Infant, Newborn Male Microbial drug resistance Microbial Sensitivity Tests Middle Aged Mycobacterium tuberculosis - physiology Pakistan - epidemiology Prevalence Retreatment Tuberculosis Tuberculosis, Multidrug-Resistant - drug therapy Tuberculosis, Multidrug-Resistant - epidemiology Young Adult
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Zusammenfassung:	To determine the prevalence and resistance pattern of multidrug-resistant tuberculosis. This cross-sectional study was carried out from January 2010 to June 2014 in nine tertiary care hospitals implementing programmatic management of drug-resistant tuberculosis in Punjab, and comprised retreatment tuberculosis cases. Data was collected from the Electronic Nominal Review System. SPSS 17 was used for data analysis. Of the 1,250 cases, 861(69%) were of multidrug-resistant tuberculosis confirmed through drug sensitivity testing. The mean age was 32 (±13.5 SD) years. Besides, 664(53%) were males and 1,208(97%) resided in urban areas of Punjab. Multidrug-resistant tuberculosis was found to be more prevalent in the most productive age group, i.e. 15-45 years, with 709(57%) cases (p
ISSN:	0030-9982