Sibling assessment based on likelihood ratio and total number of shared alleles using 21 short tandem repeat loci included in the GlobalFiler™ kit

Sibling assessment based on likelihood ratio and total number of shared alleles using 21 short tandem repeat loci included in the GlobalFiler™ kit

Highlights • The LR and the total number of shared alleles (TNSA) were investigated for sibship determination using the Identifiler and the GlobalFiler when comparing an unidentified party to an alleged sibling. • There are 3 advantages to TNSA: (1) calculations are not necessary; (2) results are ea...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Legal medicine (Tokyo, Japan) Japan), 2016-03, Vol.19, p.122-126
Hauptverfasser: Inoue, Hiroyuki, Manabe, Sho, Fujii, Koji, Iwashima, Yasuki, Miyama, Saori, Tanaka, Ayako, Saitoh, Hisako, Iwase, Hirotaro, Tamaki, Keiji, Sekiguchi, Kazumasa
Format: Artikel
Sprache:eng
Schlagworte:
Alleles
DNA Fingerprinting
Forensic science
Genetic Linkage
Genotype
GlobalFiler kit
Humans
Identifiler kit
Internal Medicine
Likelihood Functions
Likelihood ratio (LR)
Microsatellite Repeats - genetics
Polymerase Chain Reaction
Siblings
Sibship determination
Total number of shared alleles (TNSA)
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:Highlights • The LR and the total number of shared alleles (TNSA) were investigated for sibship determination using the Identifiler and the GlobalFiler when comparing an unidentified party to an alleged sibling. • There are 3 advantages to TNSA: (1) calculations are not necessary; (2) results are easily obtained by counting; and (3) results are understandable. • We propose combining the TNSA with the LR to aid in the identification of siblings.
ISSN:1344-6223
1873-4162
DOI:10.1016/j.legalmed.2015.07.008