Think You Know How Smell Works? Sniff Again

Think You Know How Smell Works? Sniff Again

The sense of smell is mediated by GPCRs in the odorant receptor (OR) family. Greer et al. report a new family of odor detectors, MS4As, that have similar cellular localization and chemodetection ability as ORs but are not GPCRs and follow a strikingly different logic of odor coding at the periphery....

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Veröffentlicht in:Cell 2016-06, Vol.165 (7), p.1566-1567
Hauptverfasser: Dey, Sandeepa, Stowers, Lisa
Format: Artikel
Sprache:eng
Schlagworte:
Humans
Odorants
Receptors, Odorant
Sensation
Smell
Thinking
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Beschreibung
Zusammenfassung:The sense of smell is mediated by GPCRs in the odorant receptor (OR) family. Greer et al. report a new family of odor detectors, MS4As, that have similar cellular localization and chemodetection ability as ORs but are not GPCRs and follow a strikingly different logic of odor coding at the periphery. The sense of smell is mediated by GPCRs in the odorant receptor (OR) family. Greer et al. report a new family of odor detectors, MS4As, that have similar cellular localization and chemodetection ability as ORs but are not GPCRs and follow a strikingly different logic of odor coding at the periphery.
ISSN:0092-8674
1097-4172
DOI:10.1016/j.cell.2016.06.006