Toward a structural understanding of co-translational protein translocation
Highlights • Advances in cryo-electron microscopy allow analysis of low abundance native complexes. • Near-atomic resolution structures of intermediates in co-translational translocation. • Cryo-electron tomography reveals translocon structure in its native lipid environment.
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| Veröffentlicht in: | Current opinion in cell biology 2016-08, Vol.41, p.91-99 |
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| container_title | Current opinion in cell biology |
| container_volume | 41 |
| creator | Voorhees, Rebecca M Hegde, Ramanujan S |
| description | Highlights • Advances in cryo-electron microscopy allow analysis of low abundance native complexes. • Near-atomic resolution structures of intermediates in co-translational translocation. • Cryo-electron tomography reveals translocon structure in its native lipid environment. |
| doi_str_mv | 10.1016/j.ceb.2016.04.009 |
| format | Article |
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| ispartof | Current opinion in cell biology, 2016-08, Vol.41, p.91-99 |
| issn | 0955-0674 1879-0410 |
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| source | MEDLINE; Elsevier ScienceDirect Journals Complete |
| subjects | Animals Internal Medicine Intracellular Membranes - metabolism Protein Transport Proteins - chemistry Proteins - metabolism Secretory Pathway Signal Recognition Particle - chemistry Signal Recognition Particle - metabolism Translocation, Genetic |
| title | Toward a structural understanding of co-translational protein translocation |
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