Human age estimation from blood using mRNA, DNA methylation, DNA rearrangement, and telomere length

Highlights • Estimating a person’s age from blood left at a crime scene provides crucial forensic information. • We studied the age effect of mRNA, DNA methylation, sjTREC, telomere length in blood. • Genome-wide marker search was followed by rigorous technical and biological validations. • Overall,...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Forensic science international : genetics 2016-09, Vol.24, p.33-43
Hauptverfasser:	Zubakov, Dmitry, Liu, Fan, Kokmeijer, Iris, Choi, Ying, van Meurs, Joyce B.J, van IJcken, Wilfred F.J, Uitterlinden, André G, Hofman, Albert, Broer, Linda, van Duijn, Cornelia M, Lewin, Jörn, Kayser, Manfred
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Aging - genetics Biomarkers - blood Blood biomarkers Blood Chemical Analysis CpG Islands - genetics DNA Methylation Forensic Gene expression Gene Expression Profiling Gene Rearrangement Human age estimation Humans Male Microarray Analysis Middle Aged mRNA Pathology Polymerase Chain Reaction RNA, Messenger - genetics sjTREC Telomere - genetics Telomere length Young Adult
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!