A novel cell culture model as a tool for forensic biology experiments and validations

Highlights • An experimental model based on cultured human dermal fibroblasts was developed. • This model involves low variance and simplifies the design of touch DNA experiments. • Comparative tape-lifting and UV decontamination studies were carried out. • Owing to the low variance reference materi...

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Veröffentlicht in:	Forensic science international : genetics 2016-09, Vol.24, p.114-119
Hauptverfasser:	Feine, Ilan, Shpitzen, Moshe, Roth, Jonathan, Gafny, Ron
Format:	Artikel
Sprache:	eng
Schlagworte:	Cell culture Cells, Cultured DNA - isolation & purification DNA Fingerprinting Experimental model Fibroblasts - cytology Humans Microsatellite Repeats Models, Biological Pathology Polymerase Chain Reaction Skin - cytology Skin cells Specimen Handling Tape-lifting Touch DNA Ultraviolet Rays UV irradiation Validations
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Zusammenfassung:	Highlights • An experimental model based on cultured human dermal fibroblasts was developed. • This model involves low variance and simplifies the design of touch DNA experiments. • Comparative tape-lifting and UV decontamination studies were carried out. • Owing to the low variance reference material, clear conclusions could be drawn.
ISSN:	1872-4973 1878-0326
DOI:	10.1016/j.fsigen.2016.06.010